Last updated on July 20th, 2021 at 09:53 pm

DMHA, also known by its trade name Octodrine, is a stimulant of the central nervous system that increases dopamine and noradrenaline. Originally sold as a decongestant, it is currently sold as a dietary supplement that is used to boost workouts, increase fat burn, and increase weight loss. While some manufacturers of the stimulant claim that it is naturally derived from aconite plants, it is more likely that the stimulant found in these dietary supplements are synthetically made in a lab. The stimulant is classified as an unsafe food additive by the FDA, and they are actively working to discontinue the manufacturing of dietary supplements that contain the stimulant. DMHA is similar to another stimulant by the name of dimethylamylamine, or DMAA.

Medical History

DMHA was studied extensively from the 1940s to 1970s, and numerous animal studies were conducted to prove its effectiveness as a decongestant. The studies also concluded that the stimulant increased the cardiac output and blood pressure of the animals. The FDA initially approved the stimulant in the 1950s for use as a decongestant. It was also approved for use in Germany as an additive to the multi-component medication Ambredin and Ordinal, but it is no longer available for use.

Beginning in the mid to late 2000s, the stimulant began appearing in dietary supplements as a boost for increasing the effectiveness of workout and fat loss. As athletes, bodybuilders, and workout enthusiasts began procuring more and more unregulated dietary supplements, the FDA began to crack down on their manufacturing and distribution. There is cause for concern that since this stimulant is so similar to DMAA, the side effects would be similar as well and just as serious. Other names that the stimulant goes by include 1,5-Diméthylhexylamine, 6-méthylheptane-2-amine, Amidrine, 2-Amino-6-methylheptane, and Kusnezoffii.

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DMHA is currently advertised as a workout and fat burner booster, but there is very little scientific evidence of the stimulant providing such benefits. Many of the stimulating benefits the drug boasts of are only seen in personal reviews of dietary supplements and can not be scientifically guaranteed. The potential benefits of the stimulant include:

  • Increased energy
  • Decreased appetite
  • Enhanced articulate speech
  • Improved memory
  • Enhanced reflexes
  • Increased mental focus
  • Improving attention deficit-hyperactive disorder, or ADHD
  • Increased athletic performance

Side Effects

DMHA is classified as an unsafe food additive by the FDA, and it is considered medically unsafe when taken by mouth. The side effects of the stimulant range from mild to severe, depending on how an individual reacts to the stimulant. It is highly advised that if an individual wishes to use the stimulant or a dietary supplement that includes it, to speak with their healthcare provider in order to do so safely.

The potential side effects of taking the stimulant can include an increase in blood pressure, constriction of the blood vessels, which could worsen some types of glaucoma, a rapid or irregular heartbeat, increasing the chance of a heart attack or stroke, increase in anxiety, trouble sleeping, chest tightness, appetite changes, shortness of breath, irritability, and jitteriness.


DMHA does not have a standard recommended dosage due to the lack of scientific evidence for its use as a dietary supplement. The right dosage for the stimulant depends on the age, health, and tolerance of the individual taking it. It is recommended to take the supplement under the guidance of a healthcare provider to ensure its safety.

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An average dosing of 50 mg to 150 mg of the stimulant, taken daily, is the amount most noted in personal reviews of the stimulant by individuals that take it to boost their workouts. In the workout and bodybuilding community, it is recommended to take the supplement between one to three hours before exercise or athletic performance to get the most out of it.


Overall, DMHA is a stimulant currently used to boost workout and athletic performances. The FDA considers the stimulant to be an unsafe food additive and is actively working to stop manufacturers from making dietary supplements with the ingredient. It is considered possibly unsafe to consume and has a range of side effects from mild to severe. It is suggested to consult with a doctor if an individual wants to try the stimulant.

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