08Dec

DMHA (Octodrine): Usage, Side Effects and Dosage

DMHA, also known by its trade name Octodrine, is a stimulant of the central nervous system that increases dopamine and noradrenaline. Originally sold as a decongestant, it is currently sold as a dietary supplement that is used to boost workouts, increase fat burn, and increase weight loss. While some manufacturers of the stimulant claim that it is naturally derived from aconite plants, it is more likely that the stimulant found in these dietary supplements are synthetically made in a lab. The stimulant is classified as an unsafe food additive by the FDA, and they are actively working to discontinue the manufacturing of dietary supplements that contain the stimulant. DMHA is similar to another stimulant by the name of dimethylamylamine, or DMAA. Medical History DMHA was studied extensively from the 1940s to 1970s, and numerous animal studies were conducted to prove its effectiveness as a decongestant. The studies also concluded that the…
08Dec

Dihexa: Usage, Side Effects and Dosage

Dihexa, also known by its developmental code name PNB-0408, is a nootropic drug derived from angiotensin IV. Angiotensin IV is a peptide hormone that affects the central nervous system and assists in the regulation of insulin and memory acquisition and recall. As a derivative of this hormone, Dihexa has been found to potentially assist in the improvement of the cognitive functions that decline as a result of Alzheimer’s disease, or other similar dementias, by augmenting synaptic connectivity. It was found to be more effective than that of brain-derived neurotrophic factor, or BDNF, and has the ability to penetrate the blood-brain barrier. Medical History Dihexa was developed by Joe Harding and Jay Wright, Professors of Neurology at Washington State University in the United States. Harding and Wright have spent 20 years researching angIV-related peptides for their procognitive effects in order to find out how they affect the hippocampus and how they…
08Dec

NSI 189: Usage, Side Effects and Dosage

NSI 189 is a neurogenic compound that is being studied for its potential as an antidepressant. The current research of the drug claims it could be a possible treatment for individuals who do not respond well to conventional antidepressant medications. The compound has gone through phase I and II clinical trials for its antidepressant properties, but the phase II trial failed to meet effectiveness outcomes. It is currently still being studied as a possible treatment for other conditions. Medical History NSI 189 is being researched by the biotechnology company Neuralstem, Inc. The company has stated that it is not only investigating the compound for use as a treatment of major depressive disorders, it is also undergoing trials for use as a treatment for Alzheimer’s disease, stroke, post-traumatic stress disorder, diabetic neuropathy, as well as cognitive impairment and decline. Research of the neurogenic compound suggests that it works by stimulating the…
08Dec

Centrophenoxine: Usage, Side Effects and Dosage

Centrophenoxine, otherwise known as Meclofenoxate or Lucidril, is a nootropic that has been studied for decades for its cognitive enhancing abilities. It is a combination of two chemicals, Dimethyl-aminoethanol, or DMAE, and Parachlorphenoxyacetic acid, or pCPA. DMAE is a substance naturally found in some fish and the human brain, and it is believed to bring on a stimulant effect over the mind. The other chemical, pCPA, is a synthetic version of a plant growth hormone. DMAE is the main component of the compound and, on its own, has trouble permeating the blood-brain barrier. When the substance is combined into Centrophenoxine, it is then able to cross the barrier and enter the brain quickly and effectively. Medical History Centrophenoxine was developed in 1959 and continues to be studied for its possible ability to improve degenerative brain disorders such as Alzheimer’s and other related dementias. The nootropic is currently able to be purchased over…
08Dec

Modafinil :Usage, Side Effects and Dosage

Modafinil is a stimulant used for treating excessive sleepiness caused by conditions such as Narcolepsy and obstructive sleep apnea. It improves the subject’s wakefulness, and that’s why it is also ommon in people experiencing shift work disorder. The drug is also known by the name Provigil. It’s an oral drug commonly found in tablet form. You should know that Modafinil does not cure the underlying cause of your excessive sleepiness. It merely helps you stay awake when you need to. This means that the underlying condition will remain unresolved, so you are bound to continue experiencing excessive sleepiness. How Does Modafinil Work? This drug’s working mechanism is not fully understood, but scientists believe that it works like armodafinil and amphetamines to stimulate the brain. It’s also possible that the drug increases dopamine levels. Dosage The Food and Drug Administration approved Modafinil in 1998. This makes it easier to acquire the…

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